izmertechИзмерительная техникаIzmeritel`naya Tekhnika0368-10252949-5237ФГУП "ВНИИФТРИ"izmertech-367Research ArticleНАНОМЕТРОЛОГИЯПрименение метода импульсной лазерной абляции для получения контрастных жидкостей на основе наночастиц оксида диспрозия Dy2O3БаршутинаМ. Н.barshutina.marie@yandex.ruБарчанскиА. .noemail@neicon.ruТамбовский государственный технический университетRussian FederationLaser Zentrum Hannover e.VRussian Federation201707022023031214Copyright © ФГУП "ВНИИФТРИ", 20232023ФГУП "ВНИИФТРИ"ФГУП "ВНИИФТРИ"https://www.izmt.ru/jour/about/submissions#copyrightNoticehttps://www.izmt.ru/jour/article/view/367

Предложен метод импульсной лазерной абляции для получения на основе наночастиц оксида диспрозия новых контрастных Т2-агентов, используемых при магнитно-резонансной томографии в больших магнитных полях. Показано, что данный метод позволяет с минимальными трудовременными затратами получать стабильные жидкости на основе наночастиц оксида диспрозия, при этом релаксивность жидкостей выше, чем большинства коммерчески доступных контрастных T2-агентов.

Pulsed laser ablation method for obtaining solutions based on Dy2O3-nanoparticles for T2 MRI contrast agents at high magnetic fields is proposed. It has been demonstrated that PLA method allows to obtain in a much easier and less time consuming way the stable Dy2O3 nanoparticle-based colloids which relaxivity exceeds the relaxivity values of commercially-available MRI contrast agents.

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The authors declare that there are no conflicts of interest present.